State of AI Agents

From Chatbots to Coworkers

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State of AI Agents 2025

The year AI stopped just “talking” and started “doing.”

If 2023 was the year of the Chatbot and 2024 was the year of the Reasoner, 2025 will be remembered as the year of the Agent.

We have crossed a threshold. We are no longer just prompting models to write poems or summarize emails. In 2025, we handed them the keyboard, the mouse, and the pipette. We moved from “Chat with your Data” to “Work with your Agent.”

From autonomous scientists to video-game-playing navigators, here is the state of AI Agents in 2025.


1. The “Action” Layer: Models That Use Computers

The most defining shift of 2025 was the move from text-generation to action-execution.

  • Claude & Computer Use: It started late in ‘24 but matured in ‘25. We saw models like Claude 3.5 and its successors gain the ability to “drive” a computer—moving cursors, clicking buttons, and navigating complex UIs just like a human.
  • OpenAI o3 & Gemini 3: The release of OpenAI’s o3 and Google’s Gemini 3 brought “deep reasoning” to agentic workflows. These models don’t just react; they plan. They generate multiple parallel solution paths, critique their own plans, and execute multi-step workflows with a reliability we hadn’t seen before.
  • The “Blue Collar” Coder: We saw the rise of “Agentic IDEs.” Tools like Google’s Jules and Antigravity didn’t just autocomplete code; they acted as asynchronous coworkers, handling entire feature requests, debugging across files, and managing deployments while the human developer slept.

2. The Autonomous Scientist

Perhaps the most profound development of 2025 was the emergence of agents in the laboratory.

  • The AI Scientist-v2: Building on earlier concepts, 2025 saw the release of systems capable of autonomously formulating hypotheses, running virtual experiments, and even writing up the results in peer-reviewed formats.
  • Wet Lab Revolution: It wasn’t just digital. We saw GPT-5 class models optimizing physical lab protocols. In one cited case, an agentic workflow redesigned a molecular cloning procedure, boosting efficiency by 79x.
  • AlphaFold’s Legacy: Marking its 5th anniversary, AlphaFold has now become the backbone of biological agents, moving from static structure prediction to dynamic interaction modeling, effectively giving biological agents a “map” of the protein universe.

3. Agents in the Wild: Gaming & Robotics

Agents broke out of the text box and into dynamic environments.

  • NitroGen: A standout paper from Nvidia/Stanford introduced NitroGen, an agent trained on 40,000+ hours of gameplay. Unlike previous bots that accessed game code, NitroGen plays via visual inputs and controller commands, just like a human. It achieved a 52% higher success rate on unseen games than scratch-trained agents, proving that “gaming intuition” is transferrable.
  • Gemini Robotics: Google’s Gemini Robotics 1.5 bridged the gap between the “mind” of an LLM and the “body” of a robot, allowing agents to navigate physical spaces and manipulate objects with unprecedented semantic understanding.

4. The Efficiency Pivot: SLMs as the “Agentic Cortex”

As discussed in our previous post on SLMs, 2025 wasn’t just about massive models. It was about Heterogeneous Agentic Systems.

We realized that using a trillion-parameter model to check a calendar is wasteful. The industry shifted toward modular architectures:

  • The Orchestrator: A massive “Reasoning Model” (like o3) creates the plan.
  • The Workers: Highly specialized Small Language Models (SLMs) execute the specific tools (API calls, data extraction) with higher accuracy and lower latency than the big models.
  • The Result: Agents that are faster, cheaper, and less prone to hallucination because the “worker” models are fine-tuned for specific tasks.

The “Trust Gap” Remains

Despite the hype, 2025 wasn’t without its hurdles. The “Cognitive Scaling Wall” became a hot topic at NeurIPS 2025. We learned that simply making agents bigger doesn’t always make them smarter at long-horizon planning.

Reliability remains the final frontier. An agent that works 90% of the time is a miracle in the lab, but a liability in production. The focus for 2026 is clear: Self-Correction. The next generation of agents won’t just be smarter; they will be humble enough to know when they’ve made a mistake and fix it before you ever notice.

Conclusion

In 2025, AI graduated from being an intern that you have to micromanage to a junior employee you can trust with a project. They are coding our software, designing our proteins, and playing our video games.

The question is no longer “What can AI generate?” The question is: “What can AI do?”


References:

  • Small Language Models for Efficient Agentic Tool Calling (Jhandi et al., 2025)
  • Small Language Models are the Future of Agentic AI (Belcak et al., 2025)
  • Google 2025 Recap: Research Breakthroughs (Google Research, Dec 2025)
  • Latest AI Research Trends 2025 (IntuitionLabs, Dec 2025)

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